Marseille coach Didier Deschamps insists his team cannot afford to play for a goalless draw in the second leg of their Europa League last-16 tie against Benfica.
Should Lyon take points off their second-placed opponents, Marseille will be able to take their first Ligue 1 title since 1992 with victory against Rennes later in the evening.
Chelsea will meet Marseille at Stamford Bridge after winning the opening game 4-1 at MSK Zilina. Marseille got off to a bad start by losing 1-0 at home to Spartak Moscow.
With both teams already qualified and Chelsea having already secured the group's top spot the game at Stade Velodrome will be all about pride. Both teams have had problems in their domestic leagues of late with Chelsea dropping into third place in the Premier League and Marseille losing top spot in Ligue 1 last weekend.
Premier League leaders Manchester United will meet defending French champions Marseille on Wednesday in one of the most interesting clashes of the Champions League first knockout round. Marseille have boosted their title chances in the Ligue 1 after grabbing three consecutive wins while Manchester United are coming from a scrappy FA Cup win against Blue Square Premier side Crawley Town.
After a goalless first leg in France Manchester United and Marseille will meet at Old Trafford on Tuesday with both sides hoping to make it to the quarter finals. Manchester United beat Arsenal 2-0 in the FA Cup last weekend while Marseille grabbed an important league win, 2-0 at second placed Rennes.
